Calosis-D Tablet: Benefits, Uses, Side Effects & Dosage

In today’s fast-paced lifestyle, many people suffer from vitamin D and calcium deficiencies due to poor diet, lack of sunlight exposure, and aging. Calosis-D Tablet is a widely prescribed supplement that helps in fulfilling the body's need for Calcium and Vitamin D3 (Cholecalciferol). This combination is essential for maintaining healthy bones, teeth, and muscles.
In this comprehensive blog, we will explore everything you need to know about Calosis-D.
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What is a Calosis-D Tablet?
Calosis-D Tablet is a nutritional supplement composed of two major ingredients:
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Vitamin D3 (Cholecalciferol) – Supports calcium absorption in the gut.
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Vitamin K2 (Menaquinone-7) – Directs calcium to bones and teeth and prevents arterial calcification.
This brings together Vitamin D3 (Cholecalciferol) and Vitamin K2 (usually as MK-7 or Menaquinone-7), which work synergistically to ensure better calcium absorption and deposition in bones rather than in arteries.
Dr. John Cannell, Founder, Vitamin D Council, said that,
“The D3-K2 duo is now considered a gold standard in bone health supplementation.”
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Why the Combination of Vitamin D3 and K2 Matters?
Recent studies show that taking only Vitamin D, especially in high yearly doses, may have side effects. Vitamin D increases the body’s need for Vitamin K2. While Vitamin D helps absorb calcium, it can't guide it to the bones. Without K2, calcium may build up in arteries, causing harmful plaques.
Dr. Kate Rheaume-Bleue, ND, Author of “Vitamin K2 and the Calcium Paradox,” highlighted that,
"Vitamin D helps your body absorb calcium, but without Vitamin K2, calcium can be deposited in the wrong places, like your arteries instead of your bones."
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Uses OF Calosis D Tablet
1. Prevents Osteoporosis
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Osteoporosis is a condition where bones become weak, porous, and more prone to fractures due to low bone density.
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Calosis-D improves calcium absorption and directs it to bones, enhancing strength and reducing fracture risk.
2. Prevents Arterial Calcification
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Arterial calcification is the buildup of calcium in blood vessel walls, leading to stiffness and reduced blood flow.
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Vitamin K2 activates Matrix Gla Protein (MGP), which prevents calcium from depositing in the arteries. This reduces the risk of atherosclerosis and heart disease.
3. Reduces Fracture Risk
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Fractures happen when bones lose strength or experience sudden force beyond their capacity, often due to low density or trauma.
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Vitamin D3 enhances calcium uptake, while K2 ensures proper mineral placement in bones, improving resilience and reducing breakage risk.
4. Enhances Calcium Absorption
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Poor calcium absorption can lead to weak bones, muscle cramps, and an increased risk of fractures or osteoporosis.
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Vitamin D3 boosts nutrient uptake from the gut, while K2 ensures efficient delivery to skeletal structures for optimal support.
5. Supports Dental Health
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Poor dental health refers to issues like cavities, gum disease, bad breath, and tooth loss caused by bacteria, plaque, or weak enamel. It can affect chewing, speech, and overall well-being if not properly managed.
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Calcium, D3, and K2 collectively support tooth remineralization, enamel repair, and healthy jawbone structure, especially during orthodontic treatments.
6. Improves Muscle Function
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Poor muscle function refers to reduced strength, coordination, or control, leading to weakness, fatigue, or limited mobility.
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Vitamin D is essential for muscle contraction and strength. Combined with K2, it helps reduce muscle cramps, weakness, and fatigue.
7. Boosts Immune System
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Weakened immunity increases the risk of infections, slow healing, and frequent illnesses. It can result from nutrient deficiencies, stress, or chronic health conditions.
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Vitamin D3 modulates immune responses, helping your body resist infections, especially respiratory ones.
8. Helpful in Managing PCOS
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Polycystic Ovary Syndrome (PCOS) is a hormonal disorder causing irregular periods, ovarian cysts, and excess androgen levels. It can lead to weight gain, acne, infertility, and insulin resistance.
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Vitamin D3 plays a role in insulin sensitivity, and K2 supports hormone balance, making Calosis-D helpful in PCOS management.
9. Supports Cognitive Health
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Cognitive functions are mental abilities like memory, attention, problem-solving, and decision-making. They help the brain process information, learn, and perform daily tasks efficiently.
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Emerging research suggests Vitamin K2 contributes to brain function by preventing oxidative stress and supporting neuron health.
10. Beneficial in Chronic Kidney Disease (CKD)
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Chronic Kidney Disease (CKD) is a long-term condition where the kidneys gradually lose their ability to filter waste and excess fluids from the blood. It can lead to high blood pressure, anemia, bone weakness, and kidney failure if not managed properly.
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Patients with CKD often suffer from calcium-phosphate imbalance. Calosis-D may help improve calcium metabolism under physician supervision.
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Side Effects of Calosis D
Calosis-D is very well tolerated; the following are the temporary side effects.
Very Common |
Rare |
Serious |
Mild nausea |
Metallic taste |
Hypercalcemia (high calcium levels) |
Headache |
Skin rash |
Calcification of soft tissues |
Upset stomach |
Fatigue |
Kidney stones |
Dosage and Administration
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Usual Adult Dose: One tablet once daily, preferably after a meal or as directed by the physician.
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Keep in Mind: Always consult your doctor before starting any supplement, especially if you're on blood thinners (e.g., warfarin), pregnant, or managing chronic conditions.
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Final Thoughts
Calosis-D combines Vitamin D3 and K2 to support strong bones, heart health, and immunity. It helps fill nutritional gaps caused by limited sun exposure and poor K2 intake. So, it is considered ideal for bone recovery, osteoporosis, or overall wellness, under medical advice.
Dr. Dennis Goodman, cardiologist, warns that.
“If you’re taking calcium or Vitamin D, make sure you’re also getting enough Vitamin K2. Without it, you might be doing more harm than good.”
If you want to learn more about your bone health, you can consult one of Pakistan’s top Orthopedic doctors or general physicians near you by visiting the website. For a quick consultation, dial 0423-2377001 and book your doctor's appointment through Apka Muaalij, the best telehealth platform in Pakistan.
FAQs (Frequently Asked Questions)
Can Calosis-D replace calcium supplements?
No, it complements calcium by improving its absorption and utilization.
Is Calosis-D safe in pregnancy?
Only take under medical supervision during pregnancy or breastfeeding.
How long should I take Calosis-D?
As prescribed, it is often long-term in bone health management.
Can I take it with multivitamins?
Yes, but avoid overdosing on fat-soluble vitamins. Always check labels.
What is the best time to take Calosis-D?
After a meal, preferably during the day for better absorption.
Does Calosis-D cause weight gain?
No, it does not impact weight.
Can diabetics take Calosis-D?
Yes, and it may even support insulin sensitivity.

Dr. Bisma Shehzadi
Dr. Bisma Shehzadi, Pharm.D, RPh, is working as a professional seasoned content writer with 4 years of experience in healthcare and wellness writing. With a strong pharmaceutical background and clinical knowledge, she creates research-driven, search-optimized articles that simplify complex medical topics. Her writing enables her to craft content that educates, promotes wellness, and supports healthcare initiatives among online users and readers.